Poster: Rapid and Efficient Genome Editing for Human Primary T-Cells

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Conclusions

• EditCo can quickly provide made-to-order edited T-cells from a variety of prevalidated donors.
• Edited T-cells retain their biologically relevant activation responses after thawing and expansion.
• T-cell pools have high editing efficiencies that are stable over time.
• EditCo T-cells have high viability and can be massively expanded by the end user.
• Both CD4+ and CD8+ cells showed only transient expression of exhaustion markers after restimulation.